Intravenous Alteplase for Stroke with Unknown Time of Onset Guided by Advanced Imaging:Systematic Review and Meta-Analysis of Individual Patient Data
Lancet 396:1574-1585, Thomalla,G.,et al, 2020
Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke
NEJM 380:1795-1803,1865, Ma, H.,et al, 2019
Extending Thrombolysis to 4.5-9 h and Wake-Up Stroke Using Perfusion Imaging: A Systematic Review and Meta-Analysis of Individual Patient Data
Lancet 394:139-147,97, Campbell, B.C.V.,et al, 2019
Treatment Concepts for Wake-Up Stroke and Stroke with Unknown Time of Symptom Onset
Stroke 46:2707-2713, Thomalla, G. & Gerloff, C., 2015
Endovascular Treatment for Acute Ischemic Stroke-Still Unproven
NEJM 368:952-955, Chimowitz,M., 2013
A Trial of Imaging Selection and Endovascular Treatment for Ischemic Stroke
NEJM 368:914-923,952, Kidwell, C.S.,et al, 2013
Advanced Brain Imaging Studies Should Be Performed in Patients With Suspected Stroke Presenting Within 4.5 Hours of Symptom Onset
Stroke 42-2666-2667,2670, Parsons, M.W., 2011
Advanced Brain Imaging Studies Should Not Be Performed in Patients With Suspected Stroke Presenting Within 4.5 Hours of Symptom Onset
Stroke 42:2668-2669,2670, Lyden, P.D., 2011
Use of MRI to Estimate the Therapeutic Window in Acute Stroke: Is Perfusion-Weighted Imaging/Diffusion-Weighted Imaging Mismatch an EPITHET for Salvageable Ischemic Brain Tissue?
Stroke 40:333-335, Toth,G. &Albers,G.W., 2009
The Ethics of Thrombolytic Trials Beyond 3 (or 4.5) Hours: Randomized Controlled Trials Are Required to Change Clinical Practice
Stroke 40:1545, Donnan,G.A. &Davis,S.M., 2009
Cost-Effectiveness of Patient Selection Using Penumbral-Based MRI for Intravenous Thrombolysis
Stroke 40:1710-1720, Earnshaw,S.R.,et al, 2009
MR Mismatch Is Useful for Patient Selection for Thrombolysis: Yes
Stroke 40:2906-2907,2910, Fiebach,J.B. &Schellinger,P.D., 2009
Rapid Assessment of Perfusion-Diffusion Mismatch
Stroke 39:75-81, Butcher,K.,et al, 2008
MR Imaging-Based Decision in Thrombolytic Therapy for Stroke on Awakening: Report of 2 Cases
AJRN 29:1314-1316, Iosif,C.,et al., 2008
Identification of the Penumbra and Infarct Core on Hyperacute Noncontrast and Perfusion CT
Neurol 68:730-736,717, Parsons,M.W.,et al, 2007
Comparison of CT Perfusion and Angiography and MRI in Selecting Stroke Patients for Acute Treatment
Neurol 68:694-697, Wintermark,M.,et al, 2007
Magnetic Resonance Perfusion Diffusion Mismatch and Thrombolysis in Acute Ischaemic Stroke: A Systematic Review of the Evidence to Date
JNNP 78:485-491,443, Kane,I.,et al, 2007
Evaluation of the Clinical-Diffusion and Perfusion-Diffusion Mismatch Models in DEFUSE
Stroke 38:1826-1830,1718, Lansberg,M.G.,et al, 2007
First-Pass Quantitiative CT Perfusion Identifies Thresholds for Salvageable Penumbra in Acute Stroke Patients Treated with Intra-arterial Therapy
AJNR 27:20-25, Schaefer,P.W.,et al, 2006
Imaging-Guided Acute Ischemic Stroke Therapy: From "Time is Brain" to "Physiology is Brain"
AJNR 27:728-735, Gonzalez,R.G., 2006
Is Penumbral Imaging Useful for Extending the Treatment Window for Intravenous Tissue Plasminogen Activator?
Ann Neurol 60:499-501, Fisher,M., 2006
Magnetic Resonance Imaging Criteria for Thrombolysis in Acute Cerebral Infarct
Stroke 36:388-397, Hjort, N., et al, 2005
Perfusion-Weighted Imaging/Diffusion-Weighted Imaging Mismatch on MRI Can Now be Used to Select Patients for Recombinant Tissue Plasminogen Activator Beyond 3 Hours
Stroke 36:1099-1100, 1100, Zivin,J.A., 2005
Perfusion-Weighted Imaging/Diffusion-Weighted Imaging Mismatch on MRI Can Now Be Used to Select Patients for Recombinant Tissue Plasminogen Activator Beyond 3 Hours
Stroke 36:1098-1099,1100, Schellinger,P.D. &Fiebach,J.B., 2005
Perfusion Computed Tomography: Prediction of Final Infarct Extent and Stroke Outcome
Ann Neurol 58:672-679,661, Parsons,M.W.,et al, 2005
The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): A Phase II MRI-Based 9-Hour Window Acute Stroke Thrombolysis Trial With Intravenous Desmoteplase
Stroke 36:66-73, Hacke,W.,et al, 2005
The Clinical-DWI Mismatch
Neurol 62:2187-2192, Davalos,A.,et al, 2004
Are There Time-Dependent Differences in Diffusion and Perfusion Within the First 6 Hours After Stroke Onset?
Stroke 35:2099, Fiehler,J.,et al, 2004
Imaging-Based Decision Making in Thrombolytic Therapy for Ischemic Stroke
Stroke 34:575-583, Schellinger,P.D.,et al, 2003
Perfusion-Weighted Magnetic Resonance Imaging Thresholds Identifying Core, Irreversibly Infarcted Tissue
Stroke 34:1425-1430, Shih,L.C.,et al, 2003
Acute Intravenou-Intra-Arterial Revascularization Therapy for Severe Ischemic Stroke
Stroke 33:279-282, Hill,M.D.,et al, 2002
Thrombolysis in Stroke Beyond Three Hours: Targeting Patients With Diffusion and Perfusion MRI
Ann Neurol 51:11-13,28, Warach,S., 2002
Thrombolytic Therapy Within 3 to 6 Hours After Onset of Ischemic Stroke
Stroke 33:1437-1441, Ringleb,P.A.,et al, 2002
Prognostic Accuracy of Cerebral Blood Flow Measurement by Perfusion Computed Tomography, at the Time of Emergency Room Admission, in Acute Stroke Patients
Ann Neurol 51:417-432,415, Wintermark,M.,et al, 2002
Comparison of Admission Perfusion Computed Tomography and Qualitative Diffusion- and Perfusion-Weighted Magnetic Resonance Imaging in Acute Stroke Patients
Stroke 33:2025-2031, Wintermark,M.,et al, 2002
Late Secondary Ischemic Injury in Patients Receiving Intraarterial Thrombolysis
Ann Neurol 52:698-703,695, Kidwell,C.S.,et al, 2002
New Imaging Strategies for Patient Selection for Thrombolytic and Neuroprotective Therapies
Neurol 57:S48-S52, Warach,S., 2001
Intra-Arterial Thrombolysis
Neurol 57:S58-S60, Saver,J.L., 2001
Diffusion-perfusion MRI Characterization of Post-recanalization Hyperperfusion in Humans
Neurol 57:2015-2021, Kidwell,C.S.,et al, 2001
Thrombolytic Reversal of Acute Human Cerebral Ischemic Injury Shown by Diffusion/Perfusion Magnetic Resonance imaging
Ann Neurol 47:462-469, Kidwell,C.S.,et al, 2000
Expanding the Window for Thrombolytic Therapy in Acute Stroke, The Potential Role of Acute MRI for Patient Selection
Stroke 30:2230-2237, Albers,G.W., 1999
MR Mismatch Is Useful for Patient Selection for Thrombolysis: No
Stroke 40:2908-2909,2910, Sch�bitz,W.R.,
Tenecteplase for Stroke - Opening the Window?
NEJM 390:760-761, Leifer,D.,, 2024
Endovascular vs Medical Management for Late Anterior Large Vessel Occlusion With Prestroke Disability
Neurol 100:e751-e763, Siegler, J.E., et al, 2023
Endovascular Therapy or Medical Management Alone for Isolated Posterior Cerebral Artery Occlusion: A Multicenter Study
Stroke 54:928-937, Sabben,C.,et al, 2023
Magnetic Resonance Imaging or Computed Tomography for Suspected Acute Stroke: Association of Admission Image Modality with Acute Recanalization Therapies, Workflow Metrics, and Outcomes
Ann Neurol 92:184-194, Fischer, U.,et al, 2022
Thrombectomy versus Medical Management in Mild Strokes due to Large Vessel Occlusion: Exploratory Analysis from the EXTEND-IA Trials and a Pooled International Cohort
Ann Neurol 92:364-378, Sarraj, A.,et al, 2022
Intravenous Thrombolysis with Tenecteplase for the Treatment of Acute Ischemic Stroke
Ann Neurol 92:349-357, Tsivgoulis, G.,et al, 2022
Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke
JAMA 325:229-231, Saver, J.L. & Adeoya, O., 2021